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Mastering Mast Cell Activation

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What you'll learn

When your mast cells aren’t behaving as they should, they can make everyday situations very challenging and even life-threatening.


Unlimited access to this easy-to-understand information – all in one place – will provide you with the resources to do your own research, in your own time. If you’re struggling and don’t know where to turn, these actionable tools and strategies will help with understanding and addressing this complicated and difficult to diagnose condition.

Ready to find relief and get on the road to complete recovery?


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With presentations from the following experts

  • Beth O'Hara, FN

    Beth O'Hara, FN

    Mastering MCAS: A Healing Journey for the Planet

    What You'll Learn

    • What is driving MCAS on a global level?
    • How to reverse hypersensitivities
    • 3 foundational steps to healing

    Visit Beth's website

  • Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Dr Kelly's Multi-Prong Approach to Healing from MCAS

    What You'll Learn

    • Why it’s important to begin with an intention to heal 
    • Accessing your intuition and interpreting the language of your body
    • Finding meaning and joy to heal from MCAS

    Visit Kelly's website

  • Jill Carnahan, MD, ABIHM, ABoIM, IFMCP

    Jill Carnahan, MD, ABIHM, ABoIM, IFMCP

    Navigating MCAS-Related Autoimmunity, Allergy, Gut and Skin Issues

    What You'll Learn

    • How MCAS influences other health conditions 
    • Most common MCAS triggers
    • Uplifting messages when facing tough times

    Visit Jill's website

  • Trudy Scott, CN

    Trudy Scott, CN

    GABA Support vs. Benzodiazepines in MCAS

    What You'll Learn

    • Benzodiazepine side effects, tapering issues and adverse effects
    • How Valium impacts DAO production 
    • GABA and other supportive nutrient dosing

    Visit Trudy's website

  • Scott Forsgren, FDN-P

    Scott Forsgren, FDN-P

    Scott’s 11 Steps for Healing with MCAS and Chronic Conditions

    What You'll Learn

    • Importance of detoxification and drainage
    • How to address hydration, KPU, mitochondrial function and more
    • EMFs, mold, pathogens and dental concerns

    Visit Scott's website

  • Elisa Song, MD

    Elisa Song, MD

    Histamine, Mast Cell Activation and Pediatric Chronic Disease

    What You'll Learn

    • Why histamine is an issue in many pediatric conditions 
    • Common MCAS and histamine triggers
    • How to strategically address these issues in children

    Visit Elisa's website

  • Nafysa Parpia, ND

    Nafysa Parpia, ND

    Managing Lyme and Mast Cells: Putting the Pieces Together

    What You'll Learn

    • What makes you more susceptible to chronic Lyme?
    • Cell danger response, MCAS and Lyme
    • Using peptides for immune response modulation and healing

    Visit Nafysa's website

  • Tania Dempsey, MD, ABIHM

    Tania Dempsey, MD, ABIHM

    Advances in Medication and Nutraceutical Approaches in Complex MCAS

    What You'll Learn

    • Strategies for sensitive individuals 
    • Lesser known MCAS treatments, including LDN protocols and peptides
    • Tier 1, 2 and 3 medication options

    Visit Tania's website

  • Beth O'Hara, FN Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Beth O'Hara, FN and Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Big Picture of MCAS and Frameworks for Healing

    What You'll Learn

    • Mast cells 101
    • Signs and symptoms 
    • Top triggers and common offenders

    Visit Beth's website

    Visit Kelly's website

  • Theo Theoharides, MS, MPhil, PhD, MD, FAAAAI

    Theo Theoharides, MS, MPhil, PhD, MD, FAAAAI

    Cutting-Edge Approaches in MCAS, COVID and Dysautonomia

    What You'll Learn

    • What is MCAS superactivation?
    • How COVID changes mast cells
    • Mast cell, dysautonomia and POTS connection

    Visit Theo's website

  • Beth O'Hara, FN

    Beth O'Hara, FN

    Cell Danger Response and Order of Operations in MCAS

    What You'll Learn

    • Why your healing protocols are failing, and what to do about it
    • Discover the approach with a 95% success rate in individuals with MCAS
    • Robust, sensitive or hypersensitive? Choosing the right protocol for your health type

    Visit Beth's website

  • Becky Campbell, DNM, DC

    Becky Campbell, DNM, DC

    Histamine Intolerance and MCAS

    What You'll Learn

    • Do you have histamine intolerance, MCAS or both? 
    • Triggers and how to address them
    • Strategies for managing histamine intolerance

    Visit Becky's website

  • Bob Miller, CTN

    Bob Miller, CTN

    Cutting-Edge Genetics in MCAS

    What You'll Learn

    • New info on ferroptosis and aryl hydrocarbon receptors 
    • Using NAD to stabilize mast cells
    • How to leverage this info to improve overall health

    Visit Bob's website

  • Andrew Salisbury

    Andrew Salisbury

    The Health-Conscious Coffee Approach with MCAS

    What You'll Learn

    • How to enjoy coffee when you have MCAS or histamine intolerance
    • Choosing the healthiest coffee possible 
    • Coffee enemas: what you need to know

    Visit Andrew's website

  • Roger Billica, MD

    Roger Billica, MD

    Easy and Highly Effective EMF Protection

    What You'll Learn

    • 3 EMF mitigation steps that can transform your health
    • How scalar energy fields can help you heal
    • Harnessing the Earth's healing magnetic fields

    Visit Roger's website

  • Arin Schultz

    Arin Schultz

    Better Sleep Hygiene

    What You'll Learn

    • Why most mattresses are a major MCAS and insomnia trigger
    • How to protect yourself from “greenwashing”
    • Sleep posture tips for individuals with EDS hypermobility, insomnia and pain

    Visit Arin's website

  • Beth O'Hara, FN

    Beth O'Hara, FN

    Mold Toxicity and MCAS Special Considerations: Salicylates, Oxalates and Sulfur Intolerance

    What You'll Learn

    • How mold toxicity and colonization affect MCAS
    • When to consider mold toxicity as a primary trigger
    • How specific intolerances can drive your symptoms

    Visit Beth's website

  • Kendra Gensemer

    Kendra Gensemer

    Safe Sauna Considerations for MCAS

    What You'll Learn

    • What to know before using a sauna if you have MCAS
    • Healing benefits, even for sensitive individuals 
    • How and when to introduce sauna into your protocol

    Visit Kendra's website

  • Christine Schaffner, ND

    Christine Schaffner, ND

    The ECCO Method for Healing MCAS

    What You'll Learn

    • How to change your biofield and heal your mast cells
    • Understanding relationships between sensitivities, energetics and empathy
    • Optimizing your lymph flow to enhance healing

    Visit Christine's website

  • Beth O'Hara, FN

    Beth O'Hara, FN

    Calming Sensitivities When Nothing Is Working

    What You'll Learn

    • Where to start when you’ve tried everything 
    • Avoiding the #1 MCAS mistake 
    • Calming mast cells when supplements and medications aren’t an option

    Visit Beth's website

  • Andrea Isaacs

    Andrea Isaacs

    Relationship Mastery in MCAS: The 5 Cs for Easing Difficult Conversations

    What You'll Learn

    • Navigating challenging conversations with your loved ones and health practitioners 
    • Resolving conflict without repressing your feelings
    • Tools for shifting neurological patterns to calm and reset your nervous system

    Visit Andrea's website

  • Mamak Shakib, DC

    Mamak Shakib, DC

    Managing Postural and Skeletal Instability in Hypermobility

    What You'll Learn

    • Using neurokinesiology to stabilize hypermobile joints
    • Why pelvic floor function is key for healing
    • Managing joint pain in hypermobile bodies

    Visit Mamak's website

  • Sunjya Schweig, MD

    Sunjya Schweig, MD

    Tick-Borne Infection Interplay with Mast Cells

    What You'll Learn

    • From immune confusion to inflammation to healing
    • Why Lyme and stealth infections are masters of evasion
    • High touch, high-tech model for healing

    Visit Sunjya's website

  • Michael Schrantz, CIEC, CMI, BPI-BA/EP

    Michael Schrantz, CIEC, CMI, BPI-BA/EP

    Addressing Environmental Mold Without Making Expensive Mistakes

    What You'll Learn

    • Top tips for finding a proficient mold inspector
    • Hidden sources of mold
    • What to do if you’re exposed to mold

    Visit Michael's website

  • Rob Downey, MD, IFMCP

    Rob Downey, MD, IFMCP

    How Can Inner Peace Reverse MCAS?

    What You'll Learn

    • Reclaiming your empowerment 
    • Measure your level of peace with these 2 tests 
    • Immediate strategies for increasing inner peace

    Visit Rob's website

  • Donald Dennis, MD, FACS

    Donald Dennis, MD, FACS

    Missing Keys in Addressing Sinus Fungal Colonization

    What You'll Learn

    • Most important strategy for fixing your health 
    • Eliminating fungal colonization and MARCoNs for good
    • Key steps for addressing mold exposure

    Visit Donald's website

  • Thomas Moorcroft, DO Darin Ingels, ND, FAAEM

    Thomas Moorcroft, DO and Darin Ingels, ND, FAAEM

    Roundtable Discussion: Tick-Borne Infections and MCAS

    What You'll Learn

    • Why tick-borne infections are major MCAS triggers
    • Why some people get Lyme and others don’t
    • How to heal from Lyme and co-infections

    Visit Thomas's website

    Visit Darin's website

  • Neil Nathan, MD

    Neil Nathan, MD

    Sensitivities Roundtable with Neil Nathan, MD

    What You'll Learn

    • Why do some people develop hypersensitivities when others don’t?
    • How to calm hypersensitivities and fight Lyme
    • Reboot your immune system

    Visit Neil's website

  • Carolyn Ledowsky, ND

    Carolyn Ledowsky, ND

    Genetic Polymorphisms, Inflammation and Histamine

    What You'll Learn

    • Link between histamine and inflammation genes and chronic disease
    • Addressing methylation blocks
    • MTHFR, fertility and methylfolate

    Visit Carolyn's website

  • Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Top MCAS Environmental Toxin Triggers

    What You'll Learn

    • Total body burden​ and the alphabet soup of chemical toxicants​
    • Relationship between multiple chemical sensitivity and MCAS
    • How genetics and environmental exposures intersect

    Visit Kelly's website

  • Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Infectious Mast Cell Triggers and MCAS Approaches

    What You'll Learn

    • Foundational information on Lyme and co-infections
    • The big 3: Borrelia, Bartonella and Babesia
    • Testing and treatment options for MCAS patients

    Visit Kelly's website

  • Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Kelly K. McCann, MD, MPH&TM, ABOIM, AFMCP

    Improving Your GI system

    What You'll Learn

    • GI mast cell triggers 
    • Relationship between histamine intolerance and MCAS
    • Choosing the right diet: low histamine, low FODMAP and more

    Visit Kelly's website

  • Christina Boyd

    Christina Boyd

    Using Brain Gym® for Whole Body/Whole Brain Integration and Healing

    What You'll Learn

    • How trauma causes physical and emotional challenges 
    • Realigning neural network dysfunction with simple movements 
    • Incorporating techniques that complement other forms of healing

    Visit Christina's website

  • Bruce Hoffman, MD

    Bruce Hoffman, MD

    Whole-Person Healing with 7 Steps of Health and Transformation

    What You'll Learn

    • Healing starts with intention and reconnecting with your true self
    • Using symptoms as a language for healing
    • Assessment and treatment strategies

    Visit Bruce's website

  • Gail Clayton, DCN, CNS, MS, RPh

    Gail Clayton, DCN, CNS, MS, RPh

    Managing MCAS and Histamine Intolerance: From Food to Phenols to Pharmaceuticals

    What You'll Learn

    • Nutritional support for histamine intolerance and methylation
    • How your diet can trigger and cure inflammation
    • Using herbs and plants to restore balance and heal

    Visit Gail's website

  • Jacob Teitelbaum, MD

    Jacob Teitelbaum, MD

    SHINE Protocol for MCAS

    What You'll Learn

    • Published studies: fatigue, fibromyalgia, long COVID and more
    • How to implement the SHINE protocol
    • Free health resources

    Visit Jacob's website

  • Jill Crista, ND

    Jill Crista, ND

    Light in the Dark for PANS and PANDAS

    What You'll Learn

    • PANS/PANDAS triggers
    • Breath to brain connection
    • 4 core treatment steps

    Visit Jill's website

  • Mary Beth Ackerley, MD, MD(H), ABIHM

    Mary Beth Ackerley, MD, MD(H), ABIHM

    Neuropsychiatric Presentations of MCAS: Oxytocin for Safety

    What You'll Learn

    • How MCAS impacts leaky brain, inflammation and the perception of danger 
    • Using brain MRI NeuroQuant as a window into limbic dysregulation 
    • Why oxytocin is the biological neuropeptide of safety

    Visit Mary Beth's website

  • Ruth Kriz, APRN

    Ruth Kriz, APRN

    Mast Cells, Biofilms and Hypercoagulability: Links Between Infections, Inflammation and Clotting

    What You'll Learn

    • How inflammation and MCAS activate blood clotting
    • Genetic clotting risks that enhance biofilm development 
    • Why microclots may contribute to MCAS symptoms

    Visit Ruth's website

  • Tom O'Bryan, DC, CCN, DACBN

    Tom O'Bryan, DC, CCN, DACBN

    Mast Cell Activation Syndrome and Autoimmunity

    What You'll Learn

    • Overview of normal and dysfunctional immune function
    • Why genetics and environmental exposures create immune dysfunction
    • Uncovering your triggers to create the best path to healing

    Visit Tom's website

  • Cathleen King, DPT

    Cathleen King, DPT

    Limbic System, MCS and MCAS

    What You'll Learn

    • How MCAS impacts the nervous system
    • Stress triggers that can lead to MCAS
    • How to develop a better sense of inner safety

    Visit Cathleen's website

  • Steve Wright

    Steve Wright

    Paraprobiotics for Retraining Immune System and Mast Cell Expression

    What You'll Learn

    • What are paraprobiotics?
    • Benefits for allergies, food sensitivities and skin issues
    • Modulating neuroinflammation with paraprobitics

    Visit Steve's website

  • Lyn Patrick, ND

    Lyn Patrick, ND

    Total Body Burden of Environmental Chemicals and MCAS

    What You'll Learn

    • Total body burden: What is it, and how does it impact mast cells?
    • Importance of clean air, water and food
    • Creating a bedroom oasis

    Visit Lyn's website

  • Lawrence Afrin, MD

    Lawrence Afrin, MD

    Origin Story: Discovery of Mast Cell Activation Syndrome

    What You'll Learn

    • Why solving medical mysteries requires patience and persistence
    • Importance of exploring every option to find real answers 
    • 3-P approach to healing

    Visit Lawrence's website

  • Jenny Johnson, PT, FMCHC, NBC-HWC

    Jenny Johnson, PT, FMCHC, NBC-HWC

    Why Recovery from Chronic Illness and CIRS Takes a Village

    What You'll Learn

    • Power of cultivating an inner terrain conducive to healing
    • Value of supportive community for navigating chronic illness
    • Common features of people who recover and obstacles to recovery

    Visit Jenny's website

  • Jeffrey Smith

    Jeffrey Smith

    How GMO Foods and Pesticides Impact MCAS

    What You'll Learn

    • Defining GMO foods, and why you should care 
    • GI manifestations of eating GMOs
    • How to avoid toxins and reduce allergies and autoimmune diseases

    Visit Jeffrey's website

  • Dayan Goodenowe, PhD

    Dayan Goodenowe, PhD

    Resolving Neuroinflammation in MCAS

    What You'll Learn

    • Overview of brain anatomy: What happens in an inflamed brain
    • Restoring mitochondria and neutralizing membrane damage
    • Healing myelin and enhancing cognition

    Visit Dayan's website

  • Amber Walker, PT, DPT, CFMP, CNPT

    Amber Walker, PT, DPT, CFMP, CNPT

    MCAS and Connective Tissue Disorders: Healing the Terrain

    What You'll Learn

    • Symptoms and causes of connective tissue dysfunction 
    • Methods for addressing the internal terrain in MCAS and EDS
    • Step-by-step process for healing

    Visit Amber's website

  • Leonard Weinstock, MD, FACG

    Leonard Weinstock, MD, FACG

    Sorting Out GI Symptoms in MCAS, POTS and Dysmotility

    What You'll Learn

    • Why MCAS is such a mystery to most physicians 
    • What is REALLY going on when you get bloated?
    • Treatment tips for stubborn GI symptoms

    Visit Leonard's website

  • Alison Vickery, FDN-P

    Alison Vickery, FDN-P

    From Dysregulation to Regulation

    What You'll Learn

    • How autoimmunity, sensitivities and autonomic nervous system are links
    • How to unblock dysregulated immune cells
    • What to do when thyroid, other hormones, A1C, and blood pressure aren't improving

    Visit Alison's website

  • Kevin Ellis, CHC

    Kevin Ellis, CHC

    Reversing Osteoporosis and Osteopenia

    What You'll Learn

    • The most important testing panel to get now for bone health
    • The risks and side effects of conventional treatments
    • Best foods, supplements, and forms of exercise to support bone health

    Visit Kevin's website

  • Allison Siebecker, ND, MSOM, LAc

    Allison Siebecker, ND, MSOM, LAc

    The Intersection of SIBO and MCAS: Histamine, Biome and Biofilms

    What You'll Learn

    • How SIBO can trigger and worsen MCAS
    • Can dysautonomia and connective tissue disorders contribute to SIBO?
    • Causes, targeted treatments and possibly a cure!

    Visit Allison's website

  • Andrew J. Maxwell, MD, FACC

    Andrew J. Maxwell, MD, FACC

    The Intersection of MCAS, hEDS and Dysautonomia: Spiky-Leaky Syndrome

    What You'll Learn

    • Link between dysautonomia, MCAS and hypermobile Ehlers-Danlos syndrome (hEDS) 
    • How these conditions can lead to craniocervical instability and airway loss
    • Understanding spiky-leaky syndrome and how to address it

    Visit Andrew's website


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As a functional and integrative physician, Dr. Kelly McCann utilizes her extensive knowledge of root causes in her thriving practice in Orange County, CA. She lectures regularly at professional conferences and is on the board of directors for two professional organizations. A graduate of Tulane University School of Medicine and School of Public Health, Dr. McCann completed a combined residency program in internal medicine and pediatrics in Arizona. She holds board certification in integrative medicine from the University of Arizona, as well as board certifications in functional medicine and medical acupuncture, and a master’s degree in spiritual psychology. She was the host of Many Manifestations of Mast Cell Activation Syndrome Summit and a co-host of the Allergy and Asthma Summit. She lives in Laguna Niguel, CA, with her husband. 

Beth O'Hara, FN

Beth O'Hara, FN

Beth O’Hara is a functional naturopathic consultant, specializing in complex, chronic cases of mast cell activation syndrome (MCAS), histamine intolerance, mold toxicity and related conditions. She is the founder and clinical director of Mast Cell 360, a functional naturopathy practice designed to look at all factors surrounding health conditions – genetic, epigenetic, biochemical, physiological, environmental and emotional.

She designed Mast Cell 360 to be the kind of practice she wished had existed when she was severely ill with MCAS, histamine intolerance, mold toxicity, neural inflammation, Lyme, fibromyalgia and chronic fatigue. Her mission today is to be a guiding light for others with these and other related conditions on their healing journeys.

Used exclusively by the practitioners at Mast Cell 360 to build personalized, effective roadmaps for healing, her MC360 method has now helped thousands of people with MCAS, mold toxicity and sensitivities to regain their lives, hopes and dreams.

O’Hara holds a doctorate in functional naturopathy, a master's degree in marriage and family therapy and a bachelor's degree in physiological psychology. She is certified in Functional Genomic Analysis and is a research adviser for the Nutrigenetic Research Institute. She presents at functional medicine conferences on MCAS and mold toxicity as well as the use of genetics and biochemistry in addressing chronic health conditions.

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